Rabbit MD-1 / LY86 Polyclonal Antibody | anti-MD-1 antibody

Rabbit Polyclonal to Human MD-1 / LY86

Cat. Num. AAA241291

• Gene Names: LY86; MD1; MD-1; MMD-1; dJ80N2.1
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: MD-1 / LY86; Polyclonal Antibody; Rabbit Polyclonal to Human MD-1 / LY86; Anti-MD-1 / LY86 Antibody (Internal) IHC-plus; LY86; DJ80N2.1; Ly-86; MD1; MD-1; RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1; Lymphocyte antigen 86; Human MD-1; anti-MD-1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: 15 amino acid peptide from near the center of human MD-1
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 162

• Applicable Applications for anti-MD-1 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB (1 - 2 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human LY86 / MD-1.
• Immunogen Type: Synthetic peptide
• Immunogen: MD-1 / LY86 antibody was raised against synthetic peptide from human LY86 / MD-1.
• Antigen Modification: Internal
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-LY86 / MD-1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of MD-1 in Daudi cell lysate with MD-1 antibody at (A) 1 and (B) 2 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 4758708
• NCBI GeneID: 9450
• NCBI Accession #: NP_004262.1
• NCBI GenBank Nucleotide #: NM_004271.3
• UniProt Accession #: O95711; Q9UQC4
• Molecular Weight: 17,906 Da
• NCBI Official Full Name: lymphocyte antigen 86
• NCBI Official Synonym Full Names: lymphocyte antigen 86
• NCBI Official Symbol: LY86
• NCBI Official Synonym Symbols: MD1; MD-1; MMD-1; dJ80N2.1
• NCBI Protein Information: lymphocyte antigen 86; ly-86; protein MD-1; MD-1, RP105-associated
• UniProt Protein Name: Lymphocyte antigen 86
• UniProt Gene Name: LY86
• UniProt Synonym Gene Names: MD1; Ly-86
• UniProt Entry Name: LY86_HUMAN

Uniprot Description

LY86: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.

Protein type: Secreted, signal peptide; Secreted; Apoptosis

Chromosomal Location of Human Ortholog: 6p25.1

Cellular Component: extracellular space; plasma membrane

Biological Process: cell proliferation; apoptosis; positive regulation of lipopolysaccharide-mediated signaling pathway; innate immune response; inflammatory response; humoral immune response