Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7044652 at dilution of 1:100)
Rabbit anti-Human MCIDAS Polyclonal Antibody | anti-MCIDAS antibody
MCIDAS Antibody
Gene Names
MCIDAS; MCI; IDAS; MCIN
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
MCIDAS; Polyclonal Antibody; MCIDAS Antibody; Multicilin; Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Protein Idas; IDAS; MCI; MCIN; anti-MCIDAS antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
385
Applicable Applications for anti-MCIDAS antibody
ELISA (EIA), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Multicilin protein
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7044652 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7044652 at dilution of 1:100)
Related Product Information for anti-MCIDAS antibody
Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,720 Da
NCBI Official Full Name
multicilin
NCBI Official Synonym Full Names
multiciliate differentiation and DNA synthesis associated cell cycle protein
NCBI Official Symbol
MCIDAS
NCBI Official Synonym Symbols
MCI; IDAS; MCIN
NCBI Protein Information
multicilin
UniProt Protein Name
Multicilin
Protein Family
UniProt Gene Name
MCIDAS
UniProt Synonym Gene Names
IDAS; MCI; MCIN
UniProt Entry Name
MCIN_HUMAN
Uniprot Description
MCIDAS: Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Belongs to the geminin family. Homodimer. Interacts with GMNN; targets GMNN to the nucleus, prevents GMNN interaction with CDT1 and competes with IDAS homodimerization
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: nucleolus; nucleus
Molecular Function: identical protein binding; protein binding
Biological Process: cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of mitotic cell cycle
Research Articles on MCIDAS
Similar Products
Product Notes
The MCIDAS mcidas (Catalog #AAA7044652) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCIDAS Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCIDAS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MCIDAS mcidas for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCIDAS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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