Immunohistochemistry (IHC)
(Anti-MCHR2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit MCHR2 Polyclonal Antibody | anti-MCHR2 antibody
Rabbit Polyclonal to Human MCHR2
Gene Names
MCHR2; SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2
Reactivity
Gibbon, Gorilla, Human, MonkeyPredicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
MCHR2; Polyclonal Antibody; Rabbit Polyclonal to Human MCHR2; Anti-MCHR2 Antibody (Cytoplasmic Domain) IHC-plus; G protein-coupled receptor slt; GPRv17; GPR145; G protein-coupled receptor 145; G-protein coupled receptor 145; MCH receptor 2; MCHR-2; MCH-2R; MCH-R2; MCH2; Mch2 receptor; SLT receptor; MCH2R; SLT; Human MCHR2; anti-MCHR2 antibody
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity)
Predicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human MCHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except REEP4 (44%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
340
Applicable Applications for anti-MCHR2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (8 - 19 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MCHR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Panda, Horse, Platypus (94%); Bat, Elephant, Pig, Xenopus (88%).
Immunogen Type
Synthetic peptide
Immunogen
MCHR2 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human MCHR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Panda, Horse, Platypus (94%); Bat, Elephant, Pig, Xenopus (88%); Bovine (81%).
Antigen Modification
Cytoplasmic Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-MCHR2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MCHR2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-MCHR2 antibody
MCHR2/GPR145 is a Melanin-Concentrating Hormone Receptor. Melanin-concentrating hormone plays an important role in the control of feeding behaviors and energy metabolism. Unlike MCH1, MCH2 signaling is not sensitive to pertussis toxin, and MCH2 cannot reduce forskolin-stimulated cAMP production.
Product Categories/Family for anti-MCHR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,849 Da
NCBI Official Full Name
melanin-concentrating hormone receptor 2
NCBI Official Synonym Full Names
melanin-concentrating hormone receptor 2
NCBI Official Symbol
MCHR2
NCBI Official Synonym Symbols
SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2
NCBI Protein Information
melanin-concentrating hormone receptor 2; MCH receptor 2; G protein-coupled receptor 145; G protein-coupled receptor slt; G-protein coupled receptor 145; melanin-concentrating hormone 2
UniProt Protein Name
Melanin-concentrating hormone receptor 2
Protein Family
UniProt Gene Name
MCHR2
UniProt Synonym Gene Names
GPR145; SLT; MCH receptor 2; MCH-R2; MCHR-2; MCH2; MCH2R
UniProt Entry Name
MCHR2_HUMAN
Uniprot Description
MCHR2: Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6q16
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on MCHR2
Similar Products
Product Notes
The MCHR2 mchr2 (Catalog #AAA247050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human MCHR2 reacts with Gibbon, Gorilla, Human, Monkey Predicted Reactivity: Dog, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's MCHR2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (8 - 19 ug/ml). Researchers should empirically determine the suitability of the MCHR2 mchr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCHR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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