Western Blot (WB)
(MCAT Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCAT antibody detected the MCAT protein (arrow).)
Rabbit anti-Human MCAT Polyclonal Antibody | anti-MCAT antibody
MCAT Antibody (C-term)
Western Blot (WB)
(MCAT Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCAT antibody detected the MCAT protein (arrow).)
Western Blot (WB)
(MCAT Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCAT antibody detected the MCAT protein (arrow).)
the mitochondrion, where it catalyzes the transfer of a malonyl
group from malonyl-CoA to the mitochondrial acyl carrier protein.
The encoded protein may be part of a fatty acid synthase complex
that is more like the type II prokaryotic and plastid complexes
rather than the type I human cytosolic complex. Two transcript
variants encoding different isoforms have been found for this gene.
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Kuhl, J.E., et al. Am. J. Physiol. Endocrinol. Metab. 290 (6), E1296-E1303 (2006) :
Zhang, L., et al. J. Biol. Chem. 278(41):40067-40074(2003)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
Uniprot Description
MCAT: Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondrias. Belongs to the type II malonyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; EC 2.3.1.39; Lipid Metabolism - fatty acid biosynthesis
Chromosomal Location of Human Ortholog: 22q13.31
Cellular Component: mitochondrion
Molecular Function: transferase activity; [acyl-carrier-protein] S-malonyltransferase activity
Biological Process: metabolic process; fatty acid biosynthetic process
Research Articles on MCAT
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Product Notes
The MCAT mcat (Catalog #AAA9209351) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 316-344. The MCAT Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCAT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MCAT mcat for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCAT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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