Testing Data
Rabbit MCAM Polyclonal Antibody | anti-MCAM antibody
MCAM Antibody
Gene Names
MCAM; CD146; MUC18
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
MCAM; Polyclonal Antibody; MCAM Antibody; anti-MCAM antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 0.02% NaN3
Sequence Length
2706
Applicable Applications for anti-MCAM antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
WB: 1:500-1:1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after
Testing Data
Testing Data
Related Product Information for anti-MCAM antibody
Rabbit polyclonal MCAM (1) antibody was raised against a recombinate human MCAM protein 259-544aa (BC056418).
Product Categories/Family for anti-MCAM antibody
References
(1) Sato, A., Torii, I., Okamura, Y., et al. Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium. Mod. Pathol. 23 (11), 1458-1466 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
57,605 Da
NCBI Official Full Name
Homo sapiens melanoma cell adhesion molecule, mRNA
NCBI Official Synonym Full Names
melanoma cell adhesion molecule
NCBI Official Symbol
MCAM
NCBI Official Synonym Symbols
CD146; MUC18
NCBI Protein Information
cell surface glycoprotein MUC18
UniProt Protein Name
Cell surface glycoprotein MUC18
Protein Family
UniProt Gene Name
MCAM
UniProt Synonym Gene Names
MUC18
Uniprot Description
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Research Articles on MCAM
Similar Products
Product Notes
The MCAM mcam (Catalog #AAA858182) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCAM Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MCAM can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the MCAM mcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCAM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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