Immunohistochemistry (IHC)
(Anti-MC5 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit MC5R / MC5 Receptor Polyclonal Antibody | anti-MC5R antibody
Rabbit Polyclonal to Human MC5R / MC5 Receptor
Gene Names
MC5R; MC2
Reactivity
Chimpanzee, Gorilla, HumanPredicted Reactivity: Monkey, Mouse, Hamster (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
MC5R / MC5 Receptor; Polyclonal Antibody; Rabbit Polyclonal to Human MC5R / MC5 Receptor; Anti-MC5R / MC5 Receptor Antibody (Internal) IHC-plus; MC5R; HMC5R; MC2; MC5-R; Melanocortin 5 receptor; MC5; MC5 receptor; MC-2; Melanocortin receptor 5; Melanocortin-5 receptor; Human MC5R; MC5 Receptor; anti-MC5R antibody
Host
Rabbit
Reactivity
Chimpanzee, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Hamster (at least 90% immunogen sequence identity)
Predicted Reactivity: Monkey, Mouse, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human MC5 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
325
Applicable Applications for anti-MC5R antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubat...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubat...
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from internal region of human MC5 Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Marmoset, Mouse, Hamster, Panda (95%); Rabbit (89%).
Immunogen Type
Synthetic peptide
Immunogen
MC5R / MC5 Receptor antibody was raised against synthetic 19 amino acid peptide from internal region of human MC5 Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Marmoset, Mouse, Hamster, Panda (95%); Rabbit (89%); Rat, Dog, Bat, Opossum (84%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-MC5 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-MC5 Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-MC5R antibody
MC5R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH), and activates adenylate cyclase. This receptor controls multiple functions in the brain and in peripheral tissues, such as thermoregulation, immunomodulation, appetite control, and sexual behavior.
Product Categories/Family for anti-MC5R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,601 Da
NCBI Official Full Name
melanocortin receptor 5
NCBI Official Synonym Full Names
melanocortin 5 receptor
NCBI Official Symbol
MC5R
NCBI Official Synonym Symbols
MC2
NCBI Protein Information
melanocortin receptor 5; melanocortin-5 receptor
UniProt Protein Name
Melanocortin receptor 5
Protein Family
UniProt Gene Name
MC5R
UniProt Synonym Gene Names
MC5-R
UniProt Entry Name
MC5R_HUMAN
NCBI Description
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. [provided by RefSeq, Jun 2010]
Uniprot Description
MC5R: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 18p11.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; melanocortin receptor activity; hormone binding
Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of cAMP biosynthetic process
Research Articles on MC5R
Similar Products
Product Notes
The MC5R mc5r (Catalog #AAA243169) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human MC5R / MC5 Receptor reacts with Chimpanzee, Gorilla, Human Predicted Reactivity: Monkey, Mouse, Hamster (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's MC5R / MC5 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubat.. Researchers should empirically determine the suitability of the MC5R mc5r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MC5R / MC5 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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