Rabbit anti-Human, Mouse MBTD1 Polyclonal Antibody | anti-MBTD1 antibody

MBTD1, CT (MBTD1, MBT domain-containing protein 1)

Cat. Num. AAA6004758

• Gene Names: MBTD1; SA49P01
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: MBTD1; Polyclonal Antibody; CT (MBTD1; MBT domain-containing protein 1); Anti -MBTD1; anti-MBTD1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-MBTD1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:50-100
• Immunogen: MBTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-600 amino acids from the C-terminal region of human MBTD1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MBTD1 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the MBTD1 antibody detected the MBTD1 protein (arrow).)

Immunohistochemistry (IHC)

(MBTD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBTD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(MBTD1 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MBTD1 antibody detected the MBTD1 protein (arrow).)

Related Product Information for anti-MBTD1 antibody

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4.

Product Categories/Family for anti-MBTD1 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 158508476
• NCBI GeneID: 54799
• NCBI Accession #: NP_060113.2
• NCBI GenBank Nucleotide #: NM_017643.2
• UniProt Accession #: Q05BQ5; Q6ZVU7; Q9NXU1
• Molecular Weight: 70,547 Da
• NCBI Official Full Name: MBT domain-containing protein 1
• NCBI Official Synonym Full Names: mbt domain containing 1
• NCBI Official Symbol: MBTD1
• NCBI Official Synonym Symbols: SA49P01
• NCBI Protein Information: MBT domain-containing protein 1
• UniProt Protein Name: MBT domain-containing protein 1
• Protein Family: MBT domain-containing protein
• UniProt Gene Name: MBTD1
• UniProt Entry Name: MBTD1_HUMAN

Uniprot Description

MBTD1: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: nucleus

Molecular Function: zinc ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; embryonic skeletal development; chromatin modification