Western Blot (WB)
((0.5ug/ml) staining of human prostate lysate (35ug protein in RIPA buffer). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
Goat MARK4L Polyclonal Antibody | anti-MARK4 antibody
Goat anti-MARK4L Antibody
Western Blot: Approx 70kDa band observed in human prostate lysates (calculated MW of 75.3kDa according to NP_113605.2). Recommended concentration: 0.3-1ug/ml.
Western Blot (WB)
((0.5ug/ml) staining of human prostate lysate (35ug protein in RIPA buffer). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
Western Blot (WB)
((0.5ug/ml) staining of human prostate lysate (35ug protein in RIPA buffer). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Uniprot Description
MARK4: a member of the CAMKL family of protein kinases. Normally expressed in neural progenitors and is re-expressed in gliomas.
Protein type: CAMK group; CAMKL family; EC 2.7.11.1; Kinase, protein; MARK subfamily; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: centrosome; cytosol; microtubule cytoskeleton; microtubule organizing center; neuron projection
Molecular Function: gamma-tubulin binding; microtubule binding; protein binding; protein serine/threonine kinase activity; tau-protein kinase activity
Biological Process: microtubule bundle formation; microtubule cytoskeleton organization and biogenesis; nervous system development; protein amino acid phosphorylation
Research Articles on MARK4
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Product Notes
The MARK4 mark4 (Catalog #AAA421011) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-MARK4L Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's MARK4L can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 70kDa band observed in human prostate lysates (calculated MW of 75.3kDa according to NP_113605.2). Recommended concentration: 0.3-1ug/ml. Researchers should empirically determine the suitability of the MARK4 mark4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: IKRKPPPGCS DSPGV. It is sometimes possible for the material contained within the vial of "MARK4L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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