Western Blot (WB)
(Western blot analysis of MARK1 expression in Hela (A) whole cell lysates.)
Rabbit anti-Human, Mouse MARK1 Polyclonal Antibody | anti-MARK1 antibody
Anti-MARK1 Antibody
Gene Names
MARK1; MARK; Par1c; Par-1c
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Purified by immunogen affinity chromatography
Synonyms
MARK1; Polyclonal Antibody; Anti-MARK1 Antibody; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; anti-MARK1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of MARK1 protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
758
Applicable Applications for anti-MARK1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1/500 - 1/2000
IHC: 1/50 - 1/200
IHC: 1/50 - 1/200
Immunogen
Recombinant full length protein of human MARK1
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of MARK1 expression in Hela (A) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of MARK1 expression in Hela (A) whole cell lysates.)
Related Product Information for anti-MARK1 antibody
Rabbit polyclonal antibody to MARK1
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,911 Da
NCBI Official Full Name
serine/threonine-protein kinase MARK1 isoform 4
NCBI Official Synonym Full Names
microtubule affinity regulating kinase 1
NCBI Official Symbol
MARK1
NCBI Official Synonym Symbols
MARK; Par1c; Par-1c
NCBI Protein Information
serine/threonine-protein kinase MARK1
UniProt Protein Name
Serine/threonine-protein kinase MARK1
Protein Family
UniProt Gene Name
MARK1
UniProt Synonym Gene Names
Par-1c; Par1c
Uniprot Description
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Research Articles on MARK1
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Product Notes
The MARK1 mark1 (Catalog #AAA8292576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MARK1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MARK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000 IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the MARK1 mark1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MARK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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