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Western Blot (WB) (Western Blot analysis of MAPK8IP1 in Mouse kidney tissue using MAPK8IP1 Rabbit pAb at dilution 1/50)

Rabbit MAPK8IP1 Polyclonal Antibody | anti-MAPK8IP1 antibody

MAPK8IP1 Rabbit pAb

Gene Names
MAPK8IP1; IB1; JIP1; JIP-1; PRKM8IP
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
MAPK8IP1; Polyclonal Antibody; MAPK8IP1 Rabbit pAb; mitogen-activated protein kinase 8 interacting protein 1; IB1; JIP1; JIP-1; PRKM8IP; anti-MAPK8IP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.4mg/ml (varies by lot)
Applicable Applications for anti-MAPK8IP1 antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human MAPK8IP1
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of MAPK8IP1 in Mouse kidney tissue using MAPK8IP1 Rabbit pAb at dilution 1/50)

Western Blot (WB) (Western Blot analysis of MAPK8IP1 in Mouse kidney tissue using MAPK8IP1 Rabbit pAb at dilution 1/50)
Related Product Information for anti-MAPK8IP1 antibody
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77,524 Da
NCBI Official Full Name
C-Jun-amino-terminal kinase-interacting protein 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8 interacting protein 1
NCBI Official Symbol
MAPK8IP1
NCBI Official Synonym Symbols
IB1; JIP1; JIP-1; PRKM8IP
NCBI Protein Information
C-Jun-amino-terminal kinase-interacting protein 1; IB-1; islet-brain 1; JNK-interacting protein 1; PRKM8 interacting protein; JNK MAP kinase scaffold protein 1
UniProt Protein Name
C-Jun-amino-terminal kinase-interacting protein 1
UniProt Gene Name
MAPK8IP1
UniProt Synonym Gene Names
IB1; JIP1; PRKM8IP; JIP-1; JNK-interacting protein 1; IB-1
UniProt Entry Name
JIP1_HUMAN

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Product Notes

The MAPK8IP1 mapk8ip1 (Catalog #AAA4760713) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAPK8IP1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAPK8IP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the MAPK8IP1 mapk8ip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPK8IP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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