Western Blot (WB)
(Mouse Map4k4 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Map4k4 antibody detected the Map4k4 protein (arrow).)
Rabbit anti-Human, mouse Map4k4 Polyclonal Antibody | anti-Map4k4 antibody
Mouse Map4k4 Antibody (Center)
Western Blot (WB)
(Mouse Map4k4 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Map4k4 antibody detected the Map4k4 protein (arrow).)
Western Blot (WB)
(Mouse Map4k4 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the Map4k4 antibody detected the Map4k4 protein (arrow).)
Western Blot (WB)
(Mouse Map4k4 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Map4k4 antibody detected the Map4k4 protein (arrow).)
Western Blot (WB)
(Mouse Map4k4 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Map4k4 antibody detected the Map4k4 protein (arrow).)
Guntur, K.V., et al. J. Biol. Chem. 285(9):6595-6603(2010)
Aouadi, M., et al. Nature 458(7242):1180-1184(2009)
Wittwer, T., et al. Biochem. Biophys. Res. Commun. 371(2):294-297(2008)
Tesz, G.J., et al. J. Biol. Chem. 282(27):19302-19312(2007)
NCBI and Uniprot Product Information
Uniprot Description
HGK: a Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF-alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, STE; STE group; STE20 family; MSN subfamily
Cellular Component: cytoplasm; intracellular
Molecular Function: transferase activity; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity
Biological Process: response to stress; regulation of JNK cascade; phosphorylation; protein amino acid phosphorylation
Research Articles on Map4k4
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Product Notes
The Map4k4 map4k4 (Catalog #AAA9209594) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 506-534. The Mouse Map4k4 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Map4k4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Map4k4 map4k4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Map4k4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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