Testing Data
(Western blot analysis of MAP-1 expression in mouse small intestine tissue lysate.)
Rabbit MAP-1 Polyclonal Antibody | anti-MAP-1 antibody
MAP-1 Antibody
Gene Names
Moap1; Map-1; Pnma4; AA987038
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
MAP-1; Polyclonal Antibody; MAP-1 Antibody; MAP1; MAP1A; MAP1L; MTAP1A; FLJ77111; anti-MAP-1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
0.5 mg/ml Protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
352
Applicable Applications for anti-MAP-1 antibody
Western Blot (WB)
Application Notes
The antibody can be used for Western blotting (1-4 ?g/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls. Blocking peptide is also available (MBS843840).
Immunogen
Synthetic peptide surrounding a.a. 342 of mouse MAP-1
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
Store at -20°C. For long term storage, aliquot and freeze at –70°C. Avoid repeated freeze/defrost cycles.
Testing Data
(Western blot analysis of MAP-1 expression in mouse small intestine tissue lysate.)
Testing Data
(Western blot analysis of MAP-1 expression in mouse small intestine tissue lysate.)
Related Product Information for anti-MAP-1 antibody
Background: Human MAP-1 (Modulator of Apoptosis Protein) is a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-XL of the Bcl-2 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
modulator of apoptosis 1
NCBI Official Synonym Full Names
modulator of apoptosis 1
NCBI Official Symbol
Moap1
NCBI Official Synonym Symbols
Map-1; Pnma4; AA987038
NCBI Protein Information
modulator of apoptosis 1
UniProt Protein Name
Modulator of apoptosis 1
UniProt Gene Name
Moap1
UniProt Synonym Gene Names
MAP-1
UniProt Entry Name
MOAP1_MOUSE
Uniprot Description
MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family.
Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol; nucleus
Molecular Function: ubiquitin protein ligase binding
Biological Process: regulation of apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; apoptosis; positive regulation of apoptosis
Research Articles on MAP-1
Similar Products
Product Notes
The MAP-1 moap1 (Catalog #AAA841292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAP-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). The antibody can be used for Western blotting (1-4 ?g/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls. Blocking peptide is also available (MBS843840). Researchers should empirically determine the suitability of the MAP-1 moap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAP-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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