Rabbit Mannheimia haemolytica Leukotoxin Polyclonal Antibody | anti-lktA antibody
Rabbit anti-Mannheimia haemolytica Leukotoxin polyclonal Antibody, Biotin conjugated
Reactivity
Mannheimia haemolytica
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Mannheimia haemolytica Leukotoxin; Polyclonal Antibody; Rabbit anti-Mannheimia haemolytica Leukotoxin polyclonal Antibody; Biotin conjugated; anti-lktA antibody
Host
Rabbit
Reactivity
Mannheimia haemolytica
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
953
Applicable Applications for anti-lktA antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Biotin
Immunogen
Recombinant Mannheimia haemolytica Leukotoxin protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101,997 Da
NCBI Official Full Name
leukotoxin
NCBI Official Symbol
MHH_RS17185
NCBI Protein Information
leukotoxin
UniProt Protein Name
Leukotoxin
Protein Family
UniProt Gene Name
lktA
UniProt Synonym Gene Names
Lkt
UniProt Entry Name
LKA1A_MANHA
Uniprot Description
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca2+ and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also week hemolytic activity.
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Product Notes
The lktA lkta (Catalog #AAA1489508) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Mannheimia haemolytica Leukotoxin polyclonal Antibody, Biotin conjugated reacts with Mannheimia haemolytica and may cross-react with other species as described in the data sheet. AAA Biotech's Mannheimia haemolytica Leukotoxin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the lktA lkta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mannheimia haemolytica Leukotoxin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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