Rabbit anti-Human MANF Polyclonal Antibody | anti-MANF antibody
MANF Polyclonal Antibody
Gene Names
MANF; ARP; ARMET
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
MANF; Polyclonal Antibody; MANF Polyclonal Antibody; Arginine-rich protein; Protein ARMET; ARMET; ARP; anti-MANF antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total MANF polyclonal antibody.
Purity/Purification
Antigen Affinity Purified
Form/Format
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
185
Applicable Applications for anti-MANF antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Mesencephalic astrocyte-derived neurotrophic factor protein(25-182aa)
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human endometrial cancer using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human liver using at dilution of 1:100.)
Related Product Information for anti-MANF antibody
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Product Categories/Family for anti-MANF antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,700 Da
NCBI Official Full Name
mesencephalic astrocyte-derived neurotrophic factor
NCBI Official Synonym Full Names
mesencephalic astrocyte derived neurotrophic factor
NCBI Official Symbol
MANF
NCBI Official Synonym Symbols
ARP; ARMET
NCBI Protein Information
mesencephalic astrocyte-derived neurotrophic factor
UniProt Protein Name
Mesencephalic astrocyte-derived neurotrophic factor
Protein Family
UniProt Gene Name
MANF
UniProt Synonym Gene Names
ARMET; ARP
UniProt Entry Name
MANF_HUMAN
Uniprot Description
ARMET: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Belongs to the ARMET family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: endoplasmic reticulum; extracellular space; nucleus
Biological Process: neurite development
Disease: Pancreatic Cancer
