Rabbit anti-Human, Mouse MAK Polyclonal Antibody | anti-MAK antibody

MAK (Serine/Threonine-protein Kinase MAK, Male Germ Cell-associated Kinase, dJ417M14.2) (AP)

Cat. Num. AAA6384653

• Gene Names: MAK; RP62
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MAK; Polyclonal Antibody; MAK (Serine/Threonine-protein Kinase MAK; Male Germ Cell-associated Kinase; dJ417M14.2) (AP); anti-MAK antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MAK. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Sequence Length: 2490

• Applicable Applications for anti-MAK antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human MAK, aa1-457 (AAH39825.1).
• Immunogen Sequence: MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKPSMGVFKEKRKKDSPFRQQVKMAVISLSAHQFPTL
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(MAK rabbit polyclonal antibody. Western Blot analysis of MAK expression in mouse brain.)

Western Blot (WB)

(Western Blot analysis of MAK expression in transfected 293T cell line by MAK polyclonal antibody. Lane 1: MAK transfected lysate (52.6kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-MAK antibody

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. [provided by RefSeq]

Product Categories/Family for anti-MAK antibody

Antibodies; Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 24981043
• NCBI GeneID: 4117
• NCBI Official Full Name: Homo sapiens male germ cell-associated kinase, mRNA
• NCBI Official Synonym Full Names: male germ cell associated kinase
• NCBI Official Symbol: MAK
• NCBI Official Synonym Symbols: RP62
• NCBI Protein Information: serine/threonine-protein kinase MAK
• Protein Family: Makatoxin

NCBI Description

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]