Western Blot (WB)
(Western blot analysis of MAGT1 Antibody (N-term) in mouse NIH-3T3 cell line lysates (35ug/lane).MAGT1 (arrow) was detected using the purified Pab.)
Rabbit MAGT1 Polyclonal Antibody | anti-MAGT1 antibody
MAGT1 Antibody (N-term)
Western Blot (WB)
(Western blot analysis of MAGT1 Antibody (N-term) in mouse NIH-3T3 cell line lysates (35ug/lane).MAGT1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of MAGT1 Antibody (N-term) in mouse NIH-3T3 cell line lysates (35ug/lane).MAGT1 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(MAGT1 Antibody (N-term) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(MAGT1 Antibody (N-term) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Molinari, F., et al. Am. J. Hum. Genet. 82(5):1150-1157(2008)
Shibatani, T., et al. Biochemistry 44(16):5982-5992(2005)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]
Uniprot Description
MAGT1: May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells. Defects in MAGT1 are the cause of mental retardation X- linked type 95 (MRX95). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. In contrast to syndromic or specific X-linked mental retardation which also present with associated physical, neurological and/or psychiatric manifestations, intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation. Defects in MAGT1 are the cause of immunodeficiency X- linked with magnesium defect Epstein-Barr virus infection and neoplasia (XMEN). XMEN is a disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T- lymphocyte activation. Belongs to the OST3/OST6 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq21.1
Cellular Component: membrane; integral to plasma membrane; oligosaccharyl transferase complex; plasma membrane
Molecular Function: magnesium ion transmembrane transporter activity
Biological Process: cellular protein metabolic process; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; cognition; magnesium ion transport
Disease: Immunodeficiency, X-linked, With Magnesium Defect, Epstein-barr Virus Infection, And Neoplasia
Research Articles on MAGT1
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Product Notes
The MAGT1 magt1 (Catalog #AAA9204119) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 44-71. The MAGT1 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Chicken) and may cross-react with other species as described in the data sheet. AAA Biotech's MAGT1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the MAGT1 magt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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