Rabbit MAGI1 Polyclonal Antibody | anti-MAGI1 antibody
MAGI1 Antibody
Gene Names
MAGI1; AIP3; BAP1; WWP3; AIP-3; BAP-1; BAIAP1; MAGI-1; Magi1d; TNRC19
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
MAGI1; Polyclonal Antibody; MAGI1 Antibody; AIP 3; AIP-3; AIP3; Atrophin 1 interacting protein 3; Atrophin-1-interacting protein 3; BAI1 associated protein 1; BAI1-associated protein 1; BAIAP 1; BAIAP1; BAP 1; BAP-1; BAP1; Gukmi1; MAGI 1; MAGI-1; MAGI1_HUMAN; MAGI1c; Membrane associated guanylate kinase inverted 1; membrane associated guanylate kinase WW and PDZ domain containing 1; Membrane-associated guanylate kinase; Membrane-associated guanylate kinase inverted 1; TNRC 19; TNRC19; Trinucleotide repeat containing gene 19; Trinucleotide repeat containing gene 19 protein; Trinucleotide repeat-containing gene 19 protein; WW and PDZ domain-containing protein 1; WW domain containing protein 3; WW domain-containing protein 3; WWP 3; WWP3; anti-MAGI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
MAGI1 Antibody detects endogenous levels of MAGI1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-MAGI1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human MAGI1.
Conjugation
Unconjugated
Subunit Structure
Interacts through its WW 2 domain with SYNPO and through its PDZ 5 domain with ACTN4. Interacts with cytoplasmic domain of ADGRB1. Interacts via its WW domains with DRPLA. Interacts with ESAM, LRP2 and CXADR (By similarity). May interact with CTNNB1 (By similarity). Interacts through its PDZ 1 domain with NET1 (By similarity). Interacts with ASIC3 and AMOT. Interacts with FCHSD2. Interacts with IGSF5/JAM4 and through its PDZ 2 and 3 domains with NPHS1 forming a tripartite complex (By similarity). Interacts with DDN. Isoform 3 (via PDZ domain) interacts with RAPGEF2. Interacts with DLL1 (By similarity). Interacts with KCNJ10 and possibly with KCNJ10/KCNJ16 heterodimer; this interaction may facilitate KCNJ10/KCNJ16 potassium channel expression at the basolateral membrane in kidney tubular cells.
Tissue Specificity
Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.
Function
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
Note
Localizes to epithelial cells tight junctions.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-MAGI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
157,781 Da
NCBI Official Full Name
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform c
NCBI Official Synonym Full Names
membrane associated guanylate kinase, WW and PDZ domain containing 1
NCBI Official Symbol
MAGI1
NCBI Official Synonym Symbols
AIP3; BAP1; WWP3; AIP-3; BAP-1; BAIAP1; MAGI-1; Magi1d; TNRC19
NCBI Protein Information
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; BAI1-associated protein 1; WW domain-containing protein 3; atrophin-1-interacting protein 3; membrane-associated guanylate kinase inverted 1; trinucleotide repeat-containing gen
UniProt Protein Name
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
UniProt Gene Name
MAGI1
UniProt Synonym Gene Names
AIP3; BAIAP1; BAP1; TNRC19; AIP-3; BAP-1; MAGI-1; WWP3
UniProt Entry Name
MAGI1_HUMAN
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Product Notes
The MAGI1 magi1 (Catalog #AAA9629832) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAGI1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAGI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the MAGI1 magi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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