Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Testing Data (Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE MAGI-2 antibody diluted at 1: 1000)

Rabbit anti-Human MAGI-2 Polyclonal Antibody | anti-MAGI-2 antibody

MAGI-2 antibody

Gene Names
MAGI2; AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1
Reactivity
Human
Applications
Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
MAGI-2; Polyclonal Antibody; MAGI-2 antibody; anti-MAGI-2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 1XPBS, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
1455
Applicable Applications for anti-MAGI-2 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:3000
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide contain a sequence corresponding to a region within amino acids 1393 and 1455 of MAGI-2
Target Name
MAGI-2
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE MAGI-2 antibody diluted at 1: 1000)

Testing Data (Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE MAGI-2 antibody diluted at 1: 1000)
Related Product Information for anti-MAGI-2 antibody
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq]
Product Categories/Family for anti-MAGI-2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
157,236 Da
NCBI Official Full Name
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform 1
NCBI Official Synonym Full Names
membrane associated guanylate kinase, WW and PDZ domain containing 2
NCBI Official Symbol
MAGI2
NCBI Official Synonym Symbols
AIP1; AIP-1; ARIP1; SSCAM; MAGI-2; ACVRIP1
NCBI Protein Information
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
UniProt Protein Name
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
UniProt Gene Name
MAGI2
UniProt Synonym Gene Names
ACVRINP1; AIP1; KIAA0705; AIP-1; MAGI-2
UniProt Entry Name
MAGI2_HUMAN

NCBI Description

The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]

Uniprot Description

AIP1: a scaffold molecule at synaptic junctions that apparently couples neurotransmitter receptors and cell adhesion proteins. Contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. Contains two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. This protein is brain specific, where it appears to be widely expressed in both neurons and glia. Enhances the ability of PTEN to suppress AKT1 activation. Two splice-variant isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q21

Cellular Component: cytoplasm; dendrite; late endosome; nucleus; perinuclear region of cytoplasm; plasma membrane; postsynaptic density; protein complex; synapse; tight junction

Molecular Function: beta-1 adrenergic receptor binding; phosphatase binding; protein binding; receptor signaling complex scaffold activity; signal transducer activity; SMAD binding

Biological Process: cytoplasmic transport; negative regulation of activin receptor signaling pathway; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of protein kinase B signaling cascade; positive regulation of phosphoprotein phosphatase activity; positive regulation of receptor internalization; protein heterooligomerization; receptor clustering

Research Articles on MAGI-2

Similar Products

Product Notes

The MAGI-2 magi2 (Catalog #AAA9409448) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAGI-2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAGI-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the MAGI-2 magi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGI-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.