Western Blot (WB)
(Western blot analysis of MAGE-D1/2 in A375 cell lysate using MBS648146 at 5ug/ml. Goat anti-rabbit Ig HRP secondary antibody and ECL substrate solution were used for this test.)
Rabbit MAGED2 Polyclonal Antibody | anti-MAGED2 antibody
MAGED2 (Melanoma-associated Antigen D2, MAGE-D2 Antigen, Breast Cancer-associated Gene 1 Protein, BCG-1, 11B6, Hepatocellular Carcinoma-associated Protein JCL-1, BCG1)
Gene Names
MAGED2; 11B6; BCG1; BCG-1; HCA10; MAGE-D2
Reactivity
Canine, Equine, Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
MAGED2; Polyclonal Antibody; MAGED2 (Melanoma-associated Antigen D2; MAGE-D2 Antigen; Breast Cancer-associated Gene 1 Protein; BCG-1; 11B6; Hepatocellular Carcinoma-associated Protein JCL-1; BCG1); Anti -MAGED2 (Melanoma-associated Antigen D2; anti-MAGED2 antibody
Host
Rabbit
Reactivity
Canine, Equine, Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MAGED1 and MAGED2. Species Crossreactivity: chimpanzee, canine, equine, mouse, rat.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Applicable Applications for anti-MAGED2 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 5-7ug/ml
Dilution: Western Blot: 5-7ug/ml
Immunogen
Synthetic peptides corresponding to CEFVKQKYLDYARVPNSN and CKVQKKDPKEWAAQYR of human MAGE-D2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis of MAGE-D1/2 in A375 cell lysate using MBS648146 at 5ug/ml. Goat anti-rabbit Ig HRP secondary antibody and ECL substrate solution were used for this test.)
Western Blot (WB)
(Western blot analysis of MAGE-D1/2 in A375 cell lysate using MBS648146 at 5ug/ml. Goat anti-rabbit Ig HRP secondary antibody and ECL substrate solution were used for this test.)
Related Product Information for anti-MAGED2 antibody
MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain. Rat and mouse orthologues have been isolated. Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously. This intracellular protein shows high expression in specific brain regions and in the interstitium of testes. Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation. Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma. MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
Product Categories/Family for anti-MAGED2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64,954 Da
NCBI Official Full Name
melanoma-associated antigen D2
NCBI Official Synonym Full Names
melanoma antigen family D, 2
NCBI Official Symbol
MAGED2
NCBI Official Synonym Symbols
11B6; BCG1; BCG-1; HCA10; MAGE-D2
NCBI Protein Information
melanoma-associated antigen D2; MAGE-D2 antigen; breast cancer-associated gene 1 protein; hepatocellular carcinoma-associated protein JCL-1
UniProt Protein Name
Melanoma-associated antigen D2
Protein Family
UniProt Gene Name
MAGED2
UniProt Synonym Gene Names
BCG1; BCG-1
UniProt Entry Name
MAGD2_HUMAN
NCBI Description
This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
Tissue specificity: Widely expressed in normal tissues.
Sequence similarities: Contains 1 MAGE domain.
Research Articles on MAGED2
Similar Products
Product Notes
The MAGED2 maged2 (Catalog #AAA648146) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAGED2 (Melanoma-associated Antigen D2, MAGE-D2 Antigen, Breast Cancer-associated Gene 1 Protein, BCG-1, 11B6, Hepatocellular Carcinoma-associated Protein JCL-1, BCG1) reacts with Canine, Equine, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAGED2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 5-7ug/ml. Researchers should empirically determine the suitability of the MAGED2 maged2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGED2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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