Western Blot (WB)
(Western blot analysis of MAGEC2 expression in NIH3T3 (A) whole cell lysates.)
Rabbit MAGEC2 Polyclonal Antibody | anti-MAGEC2 antibody
MAGEC2 Antibody
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
MAGEC2; Polyclonal Antibody; MAGEC2 Antibody; Purified Polyclonal MAGEC2 Antibody; Polyclonal MAGEC2 antibody; Anti-MAGEC2 antibody; HCA587 antibody; MAGEE1 antibody; Melanoma-associated antigen C2 antibody; Cancer/testis antigen 10 antibody; CT10 antibody; Hepatocellular carcinoma-associated antigen 587 antibody; MAGE-C2 antigen antibody; MAGE-E1 antigen antibody; anti-MAGEC2 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of MAGEC2 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
373
Applicable Applications for anti-MAGEC2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
MAGEC2 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MAGEC2 as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of MAGEC2 expression in NIH3T3 (A) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of MAGEC2 expression in NIH3T3 (A) whole cell lysates.)
Related Product Information for anti-MAGEC2 antibody
MAGEC2 is proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation.
Product Categories/Family for anti-MAGEC2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
melanoma-associated antigen C2
UniProt Protein Name
Melanoma-associated antigen C2
Protein Family
UniProt Gene Name
MAGEC2
UniProt Synonym Gene Names
HCA587; MAGEE1; CT10
UniProt Entry Name
MAGC2_HUMAN
Uniprot Description
MAGE-C2: Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xq27
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; ubiquitin protein ligase binding
Biological Process: cellular protein catabolic process; positive regulation of ubiquitin-protein ligase activity
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Product Notes
The MAGEC2 magec2 (Catalog #AAA5315607) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MAGEC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the MAGEC2 magec2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAGEC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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