Western Blot (WB)
(Western blot analysis of MAD2L1BP expression in A431 cell lysate.)
Rabbit MAD2L1BP Polyclonal Antibody | anti-MAD2L1BP antibody
Anti-MAD2L1BP Rabbit pAb
Gene Names
MAD2L1BP; CMT2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Purity
Affinity Chromatography
Synonyms
MAD2L1BP; Polyclonal Antibody; Anti-MAD2L1BP Rabbit pAb; Caught by MAD2 protein; CMT2; KIAA0110; MAD2L1 binding protein; MAD2L1-binding protein; MD2BP; MGC11282; RP1-261G23.6; anti-MAD2L1BP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MAD2L1BP Antibody detects endogenous levels of MAD2L1BP
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
306
Applicable Applications for anti-MAD2L1BP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
Immunogen
A synthesized peptide derived from human MAD2L1BP
Subcellular Location
Cytoplasm; P-body
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Western Blot (WB)
(Western blot analysis of MAD2L1BP expression in A431 cell lysate.)
Western Blot (WB)
(Western blot analysis of MAD2L1BP expression in A431 cell lysate.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney, using MAD2L1BP Antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney, using MAD2L1BP Antibody.)
Related Product Information for anti-MAD2L1BP antibody
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34kDa
NCBI Official Full Name
MAD2L1-binding protein isoform 1
NCBI Official Synonym Full Names
MAD2L1 binding protein
NCBI Official Symbol
MAD2L1BP
NCBI Official Synonym Symbols
CMT2
NCBI Protein Information
MAD2L1-binding protein
UniProt Protein Name
MAD2L1-binding protein
Protein Family
UniProt Gene Name
MAD2L1BP
UniProt Synonym Gene Names
CMT2; KIAA0110
NCBI Description
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Uniprot Description
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Research Articles on MAD2L1BP
Similar Products
Product Notes
The MAD2L1BP mad2l1bp (Catalog #AAA4750414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MAD2L1BP Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAD2L1BP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200. Researchers should empirically determine the suitability of the MAD2L1BP mad2l1bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAD2L1BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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