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Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit MAD2L1/MAD2 Polyclonal Antibody | anti-MAD2L1/MAD2 antibody

Anti-MAD2L1/MAD2 Antibody

Gene Names
MAD2L1; MAD2; HSMAD2
Reactivity
Human
Predicted: Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
MAD2L1/MAD2; Polyclonal Antibody; Anti-MAD2L1/MAD2 Antibody; Rabbit Polyclonal to Human MAD2L1/MAD2; MAD2L1; HSMAD2; MAD2; MAD2-like protein 1; anti-MAD2L1/MAD2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human MAD2L1/MAD2
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Sequence Length
205
Applicable Applications for anti-MAD2L1/MAD2 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IF: 1:50-1:200
IHC: 1:50-1:200
IHC-P: 1:100
WB: 1:500-1:2000
Immunogen
Recombinant protein of human MAD2L1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunofluorescence (IF)

(Immunofluorescence analysis of U20S cells.)

Immunofluorescence (IF) (Immunofluorescence analysis of U20S cells.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U20S cell using MAD2L1 antibody. Blue: DAPI for nuclear staining.)

Immunofluorescence (IF) (Immunofluorescence analysis of U20S cell using MAD2L1 antibody. Blue: DAPI for nuclear staining.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using MAD2L1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using MAD2L1 antibody.)

Western Blot (WB)

(Western blot analysis of extracts of various cell lines.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines.)
Related Product Information for anti-MAD2L1/MAD2 antibody
Component of the spindle-assembly checkpoint that prevents the onset ofanaphase until all chromosomes are properly aligned at the metaphaseplate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 untilall chromosomes are aligned at the metaphase plate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,335 Da
NCBI Official Full Name
mitotic spindle assembly checkpoint protein MAD2A
NCBI Official Synonym Full Names
mitotic arrest deficient 2 like 1
NCBI Official Symbol
MAD2L1
NCBI Official Synonym Symbols
MAD2; HSMAD2
NCBI Protein Information
mitotic spindle assembly checkpoint protein MAD2A
UniProt Protein Name
Mitotic spindle assembly checkpoint protein MAD2A
UniProt Gene Name
MAD2L1
UniProt Synonym Gene Names
MAD2; HsMAD2; MAD2-like protein 1

NCBI Description

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]

Uniprot Description

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Research Articles on MAD2L1/MAD2

Similar Products

Product Notes

The MAD2L1/MAD2 mad2l1 (Catalog #AAA2401503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MAD2L1/MAD2 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MAD2L1/MAD2 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IF: 1:50-1:200 IHC: 1:50-1:200 IHC-P: 1:100 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MAD2L1/MAD2 mad2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAD2L1/MAD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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