Western Blot (WB)
(Western Blot:Sample: Recombinant MIP1b, Mouse.)
Rabbit Macrophage Inflammatory Protein 1 Beta (MIP1b) Polyclonal Antibody | anti-MIP1b antibody
Polyclonal Antibody to Macrophage Inflammatory Protein 1 Beta (MIP1b)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot:Sample: Recombinant MIP1b, Mouse.)
Western Blot (WB)
(Western Blot:Sample: Recombinant MIP1b, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded lung tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded lung tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Liver Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Liver Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Intestine Tissue;Primary Ab: 20ug/ml Rabbit Anti-MouseMIP1b AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Intestine Tissue;Primary Ab: 20ug/ml Rabbit Anti-MouseMIP1b AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Kidney Tissue;Primary Ab: 20ug/ml Rabbit Anti-Mouse MIP1b AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Kidney Tissue;Primary Ab: 20ug/ml Rabbit Anti-Mouse MIP1b AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
NCBI and Uniprot Product Information
Uniprot Description
CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11 C|11 51.09 cM
Cellular Component: extracellular region; extracellular space
Molecular Function: CCR chemokine receptor binding; CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; chemokine activity; cytokine activity; identical protein binding; protein binding
Biological Process: chemotaxis; G-protein coupled receptor signaling pathway; immune response; inflammatory response; leukocyte chemotaxis; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of calcium ion transport; positive regulation of calcium-mediated signaling; positive regulation of GTPase activity; positive regulation of tumor necrosis factor production; positive regulation of vascular permeability; response to toxin
Research Articles on MIP1b
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Product Notes
The MIP1b ccl4 (Catalog #AAA2004410) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Macrophage Inflammatory Protein 1 Beta (MIP1b) reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Macrophage Inflammatory Protein 1 Beta (MIP1b) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the MIP1b ccl4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Macrophage Inflammatory Protein 1 Beta (MIP1b), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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