Western Blot (WB)
(Western blot analysis of lysate from L929 cells, using MACC1 Antibody.)
Rabbit anti-Human, Mouse MACC1 Polyclonal Antibody | anti-MACC1 antibody
MACC1 Antibody
Gene Names
MACC1; 7A5; SH3BP4L
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Synonyms
MACC1; Polyclonal Antibody; MACC1 Antibody; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5; anti-MACC1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
MACC1 Antibody detects endogenous levels of MACC1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
852
Applicable Applications for anti-MACC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:10000
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1.
Immunogen Range
411-460
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Western Blot (WB)
(Western blot analysis of lysate from L929 cells, using MACC1 Antibody.)
Western Blot (WB)
(Western blot analysis of lysate from L929 cells, using MACC1 Antibody.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
96 kDa
NCBI Official Full Name
metastasis-associated in colon cancer protein 1
NCBI Official Synonym Full Names
MACC1, MET transcriptional regulator
NCBI Official Symbol
MACC1
NCBI Official Synonym Symbols
7A5; SH3BP4L
NCBI Protein Information
metastasis-associated in colon cancer protein 1
UniProt Protein Name
Metastasis-associated in colon cancer protein 1
Protein Family
UniProt Gene Name
MACC1
NCBI Description
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
Uniprot Description
Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
Research Articles on MACC1
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Product Notes
The MACC1 macc1 (Catalog #AAA9507664) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MACC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MACC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the MACC1 macc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MACC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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