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Western Blot (WB) (Anti-LYL1 Antibody (C-Term) at 1:2000 dilution + K562 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human LYL1 Polyclonal Antibody | anti-LYL1 antibody

LYL1 Antibody (C-Term)

Gene Names
LYL1; bHLHa18
Reactivity
Human
Applications
Western Blot
Synonyms
LYL1; Polyclonal Antibody; LYL1 Antibody (C-Term); Purified Rabbit Polyclonal Antibody (Pab); Protein lyl-1; Class A basic helix-loop-helix protein 18; bHLHa18; Lymphoblastic leukemia-derived sequence 1; BHLHA18; anti-LYL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Sequence Length
280
Applicable Applications for anti-LYL1 antibody
Western Blot (WB)
Application Notes
WB~~1:2000
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-LYL1 Antibody (C-Term) at 1:2000 dilution + K562 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-LYL1 Antibody (C-Term) at 1:2000 dilution + K562 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
References
Mellentin J.D.,et al.Cell 58:77-83(1989). Grimwood J.,et al.Nature 428:529-535(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,938 Da
NCBI Official Full Name
protein lyl-1
NCBI Official Synonym Full Names
lymphoblastic leukemia associated hematopoiesis regulator 1
NCBI Official Symbol
LYL1
NCBI Official Synonym Symbols
bHLHa18
NCBI Protein Information
protein lyl-1
UniProt Protein Name
Protein lyl-1
Protein Family
UniProt Gene Name
LYL1
UniProt Synonym Gene Names
BHLHA18; bHLHa18
UniProt Entry Name
LYL1_HUMAN

NCBI Description

This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010]

Uniprot Description

LYL1: A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.

Protein type: Transcription factor; DNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleus

Molecular Function: DNA binding; protein binding; protein dimerization activity

Biological Process: B cell differentiation; blood vessel maturation; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on LYL1

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Product Notes

The LYL1 lyl1 (Catalog #AAA9216957) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LYL1 Antibody (C-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LYL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB~~1:2000. Researchers should empirically determine the suitability of the LYL1 lyl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LYL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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