Rabbit anti-Human LY6G6C Polyclonal Antibody | anti-LY6G6C antibody

LY6G6C, CT (LY6G6C, C6orf24, G6C, NG24, Lymphocyte antigen 6 complex locus protein G6c) (Azide free) (HRP)

Cat. Num. AAA6317630

• Gene Names: LY6G6C; G6c; NG24; C6orf24
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: LY6G6C; Polyclonal Antibody; CT (LY6G6C; C6orf24; G6C; NG24; Lymphocyte antigen 6 complex locus protein G6c) (Azide free) (HRP); Lymphocyte antigen 6 complex locus protein G6c; anti-LY6G6C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human LY6G6C.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-LY6G6C antibody: Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-90 in the C-terminal region of human LY6G6C, Swiss/UniProt Accession: O95867.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in NCI-H292 cell line lysates (35ug/lane) usingMBS6003926. This demonstrates that MBS6003926 detected the LY6G6C protein (arrow).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph node using MBS6003926 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS6003926 for immunohistochemistry.)

Related Product Information for anti-LY6G6C antibody

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).

Product Categories/Family for anti-LY6G6C antibody

Antibodies; KIAA; orf

References

1. Bailey, S.D., et al. Diabetes Care (2010) In press: 2. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). 3. Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009). 4. Xie, T., et al. Genome Res. 13(12):2621-2636(2003). 5. Mallya, M., et al. Genomics 80(1):113-123(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 13376874
• NCBI GeneID: 80740
• NCBI Accession #: NP_079537.1
• NCBI GenBank Nucleotide #: NM_025261.2
• UniProt Accession #: O95867; Q5SRS8; Q8IY94
• Molecular Weight: 13,821 Da
• NCBI Official Full Name: lymphocyte antigen 6 complex locus protein G6c
• NCBI Official Synonym Full Names: lymphocyte antigen 6 complex, locus G6C
• NCBI Official Symbol: LY6G6C
• NCBI Official Synonym Symbols: G6c; NG24; C6orf24
• NCBI Protein Information: lymphocyte antigen 6 complex locus protein G6c; lymphocyte antigen-6 G6C
• UniProt Protein Name: Lymphocyte antigen 6 complex locus protein G6c
• Protein Family: Lymphocyte antigen 6 complex locus protein
• UniProt Gene Name: LY6G6C
• UniProt Synonym Gene Names: C6orf24; G6C; NG24; UNQ1947/PRO4430
• UniProt Entry Name: LY66C_HUMAN