Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: TM4 cells Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds)
Rabbit anti-Human, Mouse LTA4H Polyclonal Antibody | anti-LTA4H antibody
LTA4H Antibody
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
LTA4H; Polyclonal Antibody; LTA4H Antibody; Leukotriene A-4 hydrolase; leukotriene A4 hydrolase; LKHA4; LTA-4 hydrolase; LTA4; anti-LTA4H antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total LTA4H protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
611
Applicable Applications for anti-LTA4H antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
Immunohistochemistry: 1:10-1:50
Immunogen
Fusion protein of human LTA4H
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: TM4 cells Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds)
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: TM4 cells Primary antibody: 1/300 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds)
Related Product Information for anti-LTA4H antibody
LTA4H (Leukotriene A4-hydrolase) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity.As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.
Product Categories/Family for anti-LTA4H antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,852 Da
NCBI Official Full Name
leukotriene A-4 hydrolase isoform 1
NCBI Official Synonym Full Names
leukotriene A4 hydrolase
NCBI Official Symbol
LTA4H
NCBI Protein Information
leukotriene A-4 hydrolase
UniProt Protein Name
Leukotriene A-4 hydrolase
Protein Family
UniProt Gene Name
LTA4H
UniProt Synonym Gene Names
LTA4; LTA-4 hydrolase
UniProt Entry Name
LKHA4_HUMAN
Uniprot Description
LTA4H: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. Belongs to the peptidase M1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.3.2.6; Hydrolase; Lipid Metabolism - arachidonic acid
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane
Molecular Function: aminopeptidase activity; epoxide hydrolase activity; leukotriene-A4 hydrolase activity; peptidase activity; peptide binding; protein binding; zinc ion binding
Biological Process: leukotriene biosynthetic process; leukotriene metabolic process; peptide catabolic process
Similar Products
Product Notes
The LTA4H lta4h (Catalog #AAA9415273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LTA4H Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LTA4H can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500-1:2000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the LTA4H lta4h for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LTA4H, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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