Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47271(LSM10 Antibody) at dilution 1/100.(Original magnification: 200))
Rabbit anti-Human, Mouse LSM10 Polyclonal Antibody | anti-LSM10 antibody
LSM10 Antibody
Gene Names
LSM10; MST074; MSTP074
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
LSM10; Polyclonal Antibody; LSM10 Antibody; MST074; MSTP074; anti-LSM10 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total LSM10 protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.8 mg/mL (varies by lot)
Sequence Length
123
Applicable Applications for anti-LSM10 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-300
Immunogen
Fusion protein of human LSM10
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47271(LSM10 Antibody) at dilution 1/100.(Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 47271(LSM10 Antibody) at dilution 1/100.(Original magnification: 200))
Related Product Information for anti-LSM10 antibody
LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.
Product Categories/Family for anti-LSM10 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,080 Da
NCBI Official Full Name
U7 snRNA-associated Sm-like protein LSm10
NCBI Official Synonym Full Names
LSM10, U7 small nuclear RNA associated
NCBI Official Symbol
LSM10
NCBI Official Synonym Symbols
MST074; MSTP074
NCBI Protein Information
U7 snRNA-associated Sm-like protein LSm10
UniProt Protein Name
U7 snRNA-associated Sm-like protein LSm10
Protein Family
UniProt Gene Name
LSM10
Uniprot Description
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Research Articles on LSM10
Similar Products
Product Notes
The LSM10 lsm10 (Catalog #AAA9430254) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LSM10 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LSM10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-300. Researchers should empirically determine the suitability of the LSM10 lsm10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LSM10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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