Rabbit anti-Human, Mouse LRRTM1 Polyclonal Antibody | anti-LRRTM1 antibody

LRRTM1, ID (LRRTM1, Leucine-rich repeat transmembrane neuronal protein 1)

Cat. Num. AAA6009313

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: LRRTM1; Polyclonal Antibody; ID (LRRTM1; Leucine-rich repeat transmembrane neuronal protein 1); Anti -LRRTM1; anti-LRRTM1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, mouse
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-LRRTM1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:50-100
• Immunogen: LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95~125 amino acids from the Central region of human LRRTM1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in mouse brain tissue lysates (35ug/lane) using MBS6009313. LRRTM1 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis in formalin fixed and paraffin embedded brain tissue using MBS6009313 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS6009313 for immunohistochemistry.)

Related Product Information for anti-LRRTM1 antibody

LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.

Product Categories/Family for anti-LRRTM1 antibody

Antibodies; Abs to Transmembrane Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 86990456
• NCBI GeneID: 347730
• NCBI Accession #: NP_849161.2
• NCBI GenBank Nucleotide #: NM_178839.4
• UniProt Accession #: Q86UE6; Q96DN1; A8K397; D6W5K1
• Molecular Weight: 58,641 Da
• NCBI Official Full Name: leucine-rich repeat transmembrane neuronal protein 1
• NCBI Official Synonym Full Names: leucine rich repeat transmembrane neuronal 1
• NCBI Official Symbol: LRRTM1
• NCBI Protein Information: leucine-rich repeat transmembrane neuronal protein 1; leucine-rich repeat transmembrane neuronal 1 protein
• UniProt Protein Name: Leucine-rich repeat transmembrane neuronal protein 1
• Protein Family: Leucine-rich repeat transmembrane neuronal protein
• UniProt Gene Name: LRRTM1
• UniProt Entry Name: LRRT1_HUMAN

Uniprot Description

LRRTM1: May play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons. Belongs to the LRRTM family.

Protein type: Membrane protein, integral; Cell development/differentiation; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 2p12

Cellular Component: postsynaptic membrane; cell surface; growth cone; endoplasmic reticulum; axon; integral to membrane; excitatory synapse; cell junction

Biological Process: synapse organization and biogenesis; locomotory behavior; negative regulation of receptor internalization