Western Blot (WB)
(Western Blot analysis NCI-H460 cell line lysates (35ug/lane) usingMBS642090. This demonstrates the LRRC38 antibody detected the LRRC38 protein (arrow).)
Rabbit anti-Human LRRC38 Polyclonal Antibody | anti-LRRC38 antibody
LRRC38, CT (LRRC38, Leucine-rich repeat-containing protein 38, BK channel auxilliary gamma subunit LRRC38) (Biotin)
Gene Names
LRRC38; RP4-597A16.1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
LRRC38; Polyclonal Antibody; CT (LRRC38; Leucine-rich repeat-containing protein 38; BK channel auxilliary gamma subunit LRRC38) (Biotin); BK channel auxilliary gamma subunit LRRC38; anti-LRRC38 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human LRRC38.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-LRRC38 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 188-216 in the C-terminal region of human LRRC38, UniProt Accession #Q5VT99. Cellular Localization: Cell membrane, Single-pass 1 membrane protein
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis NCI-H460 cell line lysates (35ug/lane) usingMBS642090. This demonstrates the LRRC38 antibody detected the LRRC38 protein (arrow).)
Western Blot (WB)
(Western Blot analysis NCI-H460 cell line lysates (35ug/lane) usingMBS642090. This demonstrates the LRRC38 antibody detected the LRRC38 protein (arrow).)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue using 037954followed by peroxidase conjugation of the secondary antibody and DAB staining.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue using 037954followed by peroxidase conjugation of the secondary antibody and DAB staining.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of NCI-H460 cells (right histogram) using MBS642090 compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of NCI-H460 cells (right histogram) using MBS642090 compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-LRRC38 antibody
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium
Product Categories/Family for anti-LRRC38 antibody
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,082 Da
NCBI Official Full Name
leucine-rich repeat-containing protein 38
NCBI Official Synonym Full Names
leucine rich repeat containing 38
NCBI Official Symbol
LRRC38
NCBI Official Synonym Symbols
RP4-597A16.1
NCBI Protein Information
leucine-rich repeat-containing protein 38; BK channel auxiliary gamma subunit LRRC38; BK channel auxilliary gamma subunit LRRC38
UniProt Protein Name
Leucine-rich repeat-containing protein 38
Protein Family
UniProt Gene Name
LRRC38
UniProt Entry Name
LRC38_HUMAN
Uniprot Description
LRRC38: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.21
Cellular Component: integral to membrane; plasma membrane
Biological Process: ion transport
Similar Products
Product Notes
The LRRC38 lrrc38 (Catalog #AAA6317100) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRRC38, CT (LRRC38, Leucine-rich repeat-containing protein 38, BK channel auxilliary gamma subunit LRRC38) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC38 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LRRC38 lrrc38 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRC38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
