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Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using LRIG1 antibody.)

Rabbit anti-Human, Mouse LRIG1 Polyclonal Antibody | anti-LRIG1 antibody

LRIG1 Polyclonal Antibody

Gene Names
LRIG1; LIG1; LIG-1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
LRIG1; Polyclonal Antibody; LRIG1 Polyclonal Antibody; LIG1; LIG-1; anti-LRIG1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
LRIG1 polyclonal antibody detects endogenous levels of LRIG1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
1093
Applicable Applications for anti-LRIG1 antibody
Western Blot (WB)
Application Notes
WB: 1:1000-1:2000
Immunogen
Recombinant protein of human LRIG1
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using LRIG1 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cell lines, using LRIG1 antibody.)
Related Product Information for anti-LRIG1 antibody
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 160kDa
NCBI Official Full Name
leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 1
NCBI Official Synonym Full Names
leucine rich repeats and immunoglobulin like domains 1
NCBI Official Symbol
LRIG1
NCBI Official Synonym Symbols
LIG1; LIG-1
NCBI Protein Information
leucine-rich repeats and immunoglobulin-like domains protein 1
UniProt Protein Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
UniProt Gene Name
LRIG1
UniProt Synonym Gene Names
LIG1; LIG-1
UniProt Entry Name
LRIG1_HUMAN

Uniprot Description

LRIG1: a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, regulatory subunit; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p14

Cellular Component: integral to membrane

Biological Process: sensory perception of sound; otolith morphogenesis

Research Articles on LRIG1

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Product Notes

The LRIG1 lrig1 (Catalog #AAA3009583) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRIG1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LRIG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:2000. Researchers should empirically determine the suitability of the LRIG1 lrig1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRIG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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