Western Blot (WB)
(LOXL4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the LOXL4 antibody detected the LOXL4 protein (arrow).)
Rabbit anti-Human, mouse LOXL4 Polyclonal Antibody | anti-LOXL4 antibody
LOXL4 Antibody (C-term)
Western Blot (WB)
(LOXL4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the LOXL4 antibody detected the LOXL4 protein (arrow).)
Western Blot (WB)
(LOXL4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the LOXL4 antibody detected the LOXL4 protein (arrow).)
family. The prototypic member of the family is essential to the
biogenesis of connective tissue, encoding an extracellular
copper-dependent amine oxidase that catalyses the first step in the
formation of crosslinks in collagens and elastin. A highly
conserved amino acid sequence at the C-terminus end appears to be
sufficient for amine oxidase activity, suggesting that each family
member may retain this function. The N-terminus is poorly conserved
and may impart additional roles in developmental regulation,
senescence, tumor suppression, cell growth control, and chemotaxis
to each member of the family.
Sebban, S., et al. Virchows Arch. 454(1):71-79(2009)
Gorogh, T., et al. Int. J. Oncol. 33(5):1091-1098(2008)
Kim, D.J., et al. Biochem. Biophys. Res. Commun. 373(4):521-527(2008)
Weise, J.B., et al. Int. J. Oncol. 32(2):317-322(2008)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
Uniprot Description
LOXL4: May modulate the formation of a collagenous extracellular matrix. Belongs to the lysyl oxidase family.
Protein type: Secreted; Secreted, signal peptide; Oxidoreductase; EC 1.4.3.-
Chromosomal Location of Human Ortholog: 10q24
Cellular Component: extracellular space; membrane; receptor complex
Molecular Function: protein binding; copper ion binding; protein-lysine 6-oxidase activity; scavenger receptor activity
Biological Process: receptor-mediated endocytosis
Research Articles on LOXL4
Similar Products
Product Notes
The LOXL4 loxl4 (Catalog #AAA9215330) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 575-603. The LOXL4 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LOXL4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the LOXL4 loxl4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LOXL4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
