Western Blot (WB)
(LIPN Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the LIPN antibody detected the LIPN protein (arrow).)
Rabbit anti-Human LIPN Polyclonal Antibody | anti-LIPN antibody
LIPN, CT (LIPN, LIPL4, Lipase member N, Lipase-like abhydrolase domain-containing protein 4) (APC)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(LIPN Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the LIPN antibody detected the LIPN protein (arrow).)
Western Blot (WB)
(LIPN Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the LIPN antibody detected the LIPN protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011]
Uniprot Description
LIPN: Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. Defects in LIPN are the cause of ichthyosis lamellar type 4 (LI4). A non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. At birth, the skin is normal, but widespread ichthyosis develops during childhood, with evidence of hyperkeratosis and acanthosis without epidermolytic changes on skin biopsies. Belongs to the AB hydrolase superfamily. Lipase family.
Protein type: Secreted; Hydrolase; EC 3.1.1.-; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q23.31
Cellular Component: extracellular region
Molecular Function: hydrolase activity, acting on ester bonds
Biological Process: lipid catabolic process
Disease: Ichthyosis, Congenital, Autosomal Recessive 8
Research Articles on LIPN
Similar Products
Product Notes
The LIPN lipn (Catalog #AAA6316461) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIPN, CT (LIPN, LIPL4, Lipase member N, Lipase-like abhydrolase domain-containing protein 4) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LIPN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LIPN lipn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIPN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
