Rabbit anti-Human LGALS9 Polyclonal Antibody | anti-LGALS9 antibody

LGALS9, NT (LGALS9, Galectin-9, Ecalectin, Tumor antigen HOM-HD-21) (MaxLight 550)

Cat. Num. AAA6315851

• Gene Names: LGALS9; HUAT; LGALS9A
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LGALS9; Polyclonal Antibody; NT (LGALS9; Galectin-9; Ecalectin; Tumor antigen HOM-HD-21) (MaxLight 550); Tumor antigen HOM-HD-21; anti-LGALS9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

• Applicable Applications for anti-LGALS9 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LGALS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human LGALS9.
• Conjugate: MaxLight550
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-LGALS9 antibody

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Product Categories/Family for anti-LGALS9 antibody

Antibodies; Lectins

References

Dardalhon, V., et al. J. Immunol. 185(3):1383-1392(2010). Tanikawa, R., et al. Biochem. Biophys. Res. Commun. 394(2):317-322(2010). Katoh, S., et al. Int. Arch. Allergy Immunol. 153(3):294-302(2010). Niki, T., et al. J. Biol. Chem. 284(47):32344-32352(2009). Zhang, F., et al. Zhonghua Zhong Liu Za Zhi 31(2):95-98(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 102469694
• NCBI GeneID: 3965
• NCBI Accession #: NP_002299.2; NP_033665.1
• NCBI GenBank Nucleotide #: NM_002308.3
• UniProt Accession #: O00182; O14532; O75028; Q3B8N1; Q53FQ0; Q9NQ58; A7VJG6
• Molecular Weight: 39,518 Da
• NCBI Official Full Name: galectin-9 isoform short
• NCBI Official Synonym Full Names: lectin, galactoside-binding, soluble, 9
• NCBI Official Symbol: LGALS9
• NCBI Official Synonym Symbols: HUAT; LGALS9A
• NCBI Protein Information: galectin-9; gal-9; ecalectin; galectin 9; tumor antigen HOM-HD-21; urate transporter/channel protein
• UniProt Protein Name: Galectin-9
• Protein Family: Galectin
• UniProt Gene Name: LGALS9
• UniProt Synonym Gene Names: Gal-9
• UniProt Entry Name: LEG9_HUMAN

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm

Molecular Function: signal transducer activity; galactose binding; carbohydrate binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction