Rabbit anti-Pig, Human LFR Polyclonal Antibody | anti-LFR antibody
LFR polyclonal antibody
Gene Names
ITLN1; HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
Reactivity
Pig, Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Synonyms
LFR; Polyclonal Antibody; LFR polyclonal antibody; Intelectin-1; ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin; INTL; ITL; UNQ640/PRO1270; anti-LFR antibody
Host
Rabbit
Reactivity
Pig, Human
Clonality
Polyclonal
Specificity
LFR polyclonal antibody detects endogenous levels of LFR protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Applicable Applications for anti-LFR antibody
Western Blot (WB)
Application Notes
WB: 1:2000~1:5000
Immunogen
Synthetic peptide, corresponding to Human LFR.
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Related Product Information for anti-LFR antibody
Intelectin-1, also known as ITLN1, INTL, Omentin or LFR, is a 313 amino acidprotein that contains one fibrinogen C-terminal domain and is either secretedor lipid-anchored to the cell membrane. Highly expressed in small intestineand adipose tissue and present at lower levels in testis, heart, pancreas, colonand skeletal muscle, Intelectin-1 exists as a disulfide-linked homotrimer thatfunctions to enhance Insulin-stimulated glucose uptake and is also thought toparticipate in host defense against miccroorganisms. In addition to its rolesin glucose regulation and immune system function, Intelectin-1 may also beinvolved in iron metabolism and obesity regulation in adults. Intelectin-2shares 85% amino acid identity with Intelectin-1 and, like Intelectin-1, is asecreted protein that contains one fibrinogen C-terminal domain and is thoughtto play a role in the host defense system. While Intelectin-1 is present in avariety of tissues, Intelectin-2 exists only in the small intestine.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,962 Da
NCBI Official Full Name
intelectin-1
NCBI Official Synonym Full Names
intelectin 1 (galactofuranose binding)
NCBI Official Symbol
ITLN1
NCBI Official Synonym Symbols
HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
NCBI Protein Information
intelectin-1; ITLN-1; endothelial lectin HL-1; galactofuranose-binding lectin; intestinal lactoferrin receptor
UniProt Protein Name
Intelectin-1
Protein Family
UniProt Gene Name
ITLN1
UniProt Synonym Gene Names
INTL; ITLN; LFR; ITLN-1
UniProt Entry Name
ITLN1_HUMAN
Uniprot Description
ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: brush border membrane; receptor complex; lipid raft
Molecular Function: carbohydrate binding
Biological Process: positive regulation of glucose import; response to nematode; positive regulation of protein amino acid phosphorylation
Research Articles on LFR
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Product Notes
The LFR itln1 (Catalog #AAA3015852) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LFR polyclonal antibody reacts with Pig, Human and may cross-react with other species as described in the data sheet. AAA Biotech's LFR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000~1:5000. Researchers should empirically determine the suitability of the LFR itln1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LFR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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