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Rabbit anti-Mouse, Rat LEUMORPHIN Polyclonal Antibody | anti-Pdyn antibody

RABBIT ANTI LEUMORPHIN

Reactivity
Mouse, Rat
Applications
Immunohistochemistry
Synonyms
LEUMORPHIN; Polyclonal Antibody; RABBIT ANTI LEUMORPHIN; anti-Pdyn antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Form/Format
Serum
Serum - liquid
Sequence Length
248
Applicable Applications for anti-Pdyn antibody
Immunohistology Frozen
Application Notes
Immunohistology - Frozen: Minimum Dilution: 1/200; Maximum Dilution: 1/2000
Perservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
Buffer Solution
Phosphate buffered saline
Antiserum Preparation
Antisera to Leumorphin were raised by repeated immunisation of rabbits with highly purified antigen. Whole serum is supplied - diluted.
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-Pdyn antibody
Rabbit anti Leumorphin antibody recognizes rat leumorphin, also known as dynorphin B29. Leumorphin is a 28 amino acid opioid peptide resulting from cleavage of proenkephalin-B. Leumorphin positive cells are found in the paraventricular, supraoptic nucleus and fibres in the lateral hypothalamus of colchicine treated rat brain (Neal & Newman 1989). Leumorphin has been reported to exert anti-apoptotic effects in rat PC12 pheochromocytoma cells (Lee et al. 2005). Rabbit anti leumorphin has been used successfully to detect leumorphin in murine brain using immunohistochemistry on cryostat sections.(Zhang et al.2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
28,079 Da
NCBI Official Full Name
Proenkephalin-B
NCBI Official Synonym Full Names
prodynorphin
NCBI Official Symbol
Pdyn
NCBI Protein Information
proenkephalin-B; beta-neoendorphin-dynorphin; preprodynorphin; proenkephalin B
UniProt Protein Name
Proenkephalin-B
Protein Family
UniProt Gene Name
Pdyn
UniProt Synonym Gene Names
Big Dyn; Dyn-A17; Dynorphin A; Dyn-B
UniProt Entry Name
PDYN_RAT

NCBI Description

expression in hippocampus increases in response to traumatic brain injury; may play a role in regulatio of neurotransmitter release [RGD, Feb 2006]

Uniprot Description

Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress ().

Research Articles on Pdyn

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Product Notes

The Pdyn pdyn (Catalog #AAA222379) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI LEUMORPHIN reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LEUMORPHIN can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen. Immunohistology - Frozen: Minimum Dilution: 1/200; Maximum Dilution: 1/2000. Researchers should empirically determine the suitability of the Pdyn pdyn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LEUMORPHIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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