Rabbit anti-Human, Mouse LDOC1L Polyclonal Antibody | anti-LDOC1L antibody

LDOC1L, CT (LDOC1L, MAR6, MART6, Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6) (Biotin)

Cat. Num. AAA6315670

• Gene Names: LDOC1L; Mar6; Mart6; dJ1033E15.2
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LDOC1L; Polyclonal Antibody; CT (LDOC1L; MAR6; MART6; Protein LDOC1L; Leucine zipper protein down-regulated in cancer cells-like; Mammalian retrotransposon-derived protein 6) (Biotin); Mammalian retrotransposon-derived protein 6; anti-LDOC1L antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-LDOC1L antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the C-terminal region of human LDOC1L.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LDOC1L Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the LDOC1L antibody detected the LDOC1L protein (arrow).)

Related Product Information for anti-LDOC1L antibody

LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.

Product Categories/Family for anti-LDOC1L antibody

Antibodies; Cancer Markers

References

Brandt, J., et al. Gene 345(1):101-111(2005). Brandt, J., et al. Cytogenet. Genome Res. 110 (1-4), 307-317 (2005): Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004).

NCBI and Uniprot Product Information

• NCBI GI #: 49355807
• NCBI GeneID: 84247
• NCBI Accession #: NP_115663.2
• NCBI GenBank Nucleotide #: NM_032287.2
• UniProt Accession #: Q6ICC9; Q6ZTR1
• Molecular Weight: 26,154 Da
• NCBI Official Full Name: protein LDOC1L
• NCBI Official Synonym Full Names: leucine zipper, down-regulated in cancer 1-like
• NCBI Official Symbol: LDOC1L
• NCBI Official Synonym Symbols: Mar6; Mart6; dJ1033E15.2
• NCBI Protein Information: protein LDOC1L; mammalian retrotransposon-derived protein 6; leucine zipper protein down-regulated in cancer cells-like
• UniProt Protein Name: Protein LDOC1L
• Protein Family: Protein
• UniProt Gene Name: LDOC1L
• UniProt Synonym Gene Names: MAR6; MART6
• UniProt Entry Name: LDOCL_HUMAN

Uniprot Description

LDOC1L iso3:

Chromosomal Location of Human Ortholog: 22q13.31