Rabbit anti-Human LDHAL6B Polyclonal Antibody | anti-LDHAL6B antibody
LDHAL6B Antibody (NT)
Appearance: Colorless liquid
Shelf Life: 12 months
Background: L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
NCBI and Uniprot Product Information
Uniprot Description
LDHAL6B: Belongs to the LDH/MDH superfamily. LDH family.
Protein type: Oxidoreductase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; EC 1.1.1.27; Amino Acid Metabolism - cysteine and methionine
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; L-lactate dehydrogenase activity
Biological Process: cellular carbohydrate metabolic process
Research Articles on LDHAL6B
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Product Notes
The LDHAL6B ldhal6b (Catalog #AAA841252) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LDHAL6B Antibody (NT) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LDHAL6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot: ~1:1000. Researchers should empirically determine the suitability of the LDHAL6B ldhal6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LDHAL6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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