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Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with MBS7600954 (LCA5 Antibody) at dilution of 1:300)

Rabbit anti-Human LCA5 Polyclonal Antibody | anti-LCA5 antibody

LCA5 Rabbit Polyclonal

Gene Names
LCA5; C6orf152
Reactivity
Human
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
LCA5; Polyclonal Antibody; LCA5 Rabbit Polyclonal; anti-LCA5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
697
Applicable Applications for anti-LCA5 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Leber congenital amaurosis 5
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS7600954 (LCA5 Antibody) at dilution of 1:300)

Western Blot (WB) (HeLa cells were subjected to SDS PAGE followed by western blot with MBS7600954 (LCA5 Antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,554 Da
NCBI Official Full Name
lebercilin
NCBI Official Synonym Full Names
LCA5, lebercilin
NCBI Official Symbol
LCA5
NCBI Official Synonym Symbols
C6orf152
NCBI Protein Information
lebercilin
UniProt Protein Name
Lebercilin
Protein Family
UniProt Gene Name
LCA5
UniProt Synonym Gene Names
C6orf152
UniProt Entry Name
LCA5_HUMAN

NCBI Description

This gene encodes a protein that is thought to be involved in centrosomal or ciliary functions. Mutations in this gene cause Leber congenital amaurosis type V. Alternatively spliced transcript variants are described. [provided by RefSeq, Oct 2009]

Uniprot Description

LCA5: Might be involved in minus end-directed microtubule transport. Defects in LCA5 are the cause of Leber congenital amaurosis type 5 (LCA5). LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. Belongs to the LCA5 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: cilium; cytoplasm; microtubule organizing center

Molecular Function: protein binding; protein complex binding

Biological Process: protein transport

Disease: Leber Congenital Amaurosis 5

Research Articles on LCA5

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Product Notes

The LCA5 lca5 (Catalog #AAA7600954) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LCA5 Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LCA5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the LCA5 lca5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LCA5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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