Western Blot (WB)
(Western blot analysis of Lano expression in A431 cell lysate with Lano antibody at (A) 1 and (B) 2 μg/ml.)
Rabbit anti-Human Lano Polyclonal Antibody | anti-LRRC1 antibody
Lano Antibody
Gene Names
LRRC1; LANO; dJ523E19.1
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Lano Antibody is affinity chromatography purified via peptide column.
Synonyms
Lano; Polyclonal Antibody; Lano Antibody; LANO; dJ523E19.1; Leucine-rich repeat-containing protein 1; LANO adapter protein; leucine rich repeat containing 1; anti-LRRC1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Lano Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
524
Applicable Applications for anti-LRRC1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Lano antibody can be used for detection of Lano by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
Lano antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.
Buffer
Lano Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Lano antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of Lano expression in A431 cell lysate with Lano antibody at (A) 1 and (B) 2 μg/ml.)
Western Blot (WB)
(Western blot analysis of Lano expression in A431 cell lysate with Lano antibody at (A) 1 and (B) 2 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of Lano in human colon tissue with Lano antibody at 10 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of Lano in human colon tissue with Lano antibody at 10 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of Lano in human colon tissue with Lano antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of Lano in human colon tissue with Lano antibody at 20 μg/mL.)
Related Product Information for anti-LRRC1 antibody
Lano Antibody: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22,943 Da
NCBI Official Full Name
LANO adaptor protein
NCBI Official Synonym Full Names
leucine rich repeat containing 1
NCBI Official Symbol
LRRC1
NCBI Official Synonym Symbols
LANO; dJ523E19.1
NCBI Protein Information
leucine-rich repeat-containing protein 1; LANO adapter protein; LAP and no PDZ protein; leucine-rich repeat-containing 1; LAP (leucine-rich repeats and PDZ) and no PDZ protein
UniProt Protein Name
Leucine-rich repeat-containing protein 1
Protein Family
UniProt Gene Name
LRRC1
UniProt Synonym Gene Names
LANO
UniProt Entry Name
LRRC1_HUMAN
Uniprot Description
LRRC1: 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 6p12.1
Cellular Component: membrane; cytoplasm
Research Articles on LRRC1
Similar Products
Product Notes
The LRRC1 lrrc1 (Catalog #AAA150699) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lano Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lano can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Lano antibody can be used for detection of Lano by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the LRRC1 lrrc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lano, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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