Rabbit anti-Human, Mouse LAF4 Polyclonal Antibody | anti-AFF3 antibody
LAF4 Antibody (C-term)
Western Blot (WB)
(Anti-LAF4 Antibody (C-term) at 1:2000 dilution + mouse spleen lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 133 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(The anti-LAF4 Pab is used in Western blot to detect LAF4 in placenta tissue lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
AFF3: Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA. Belongs to the AF4 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 2q11.2-q12
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: double-stranded DNA binding
Biological Process: embryonic hindlimb morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on AFF3
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Product Notes
The AFF3 aff3 (Catalog #AAA9217019) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1197-1227. The LAF4 Antibody (C-term) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAF4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA. WB~~1:1000. Researchers should empirically determine the suitability of the AFF3 aff3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAF4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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