Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Lactoferrin Polyclonal Antibody | anti-LTF antibody
Polyclonal Antibody to Lactoferrin (LTF)
MGHHHHHHSGSEF-LYLG SGYFTAIQNL RKSEEEVAAR RARVVWCAVG EQELRKCNQW SGLSEGSVTC SSASTTEDCI ALVLKGEADA MSLDGGYVYT AGKCGLVPVL AENYKSQQSS DPDPNCVDR
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Description
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter.
Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: cell surface; cytoplasm; extracellular exosome; extracellular region; extracellular space; nucleus; other organism cell membrane; protein complex; secretory granule; specific granule; tertiary granule lumen
Molecular Function: cysteine-type endopeptidase inhibitor activity; DNA binding; heparin binding; iron ion binding; lipopolysaccharide binding; protein binding; protein serine/threonine kinase activator activity; serine-type endopeptidase activity
Biological Process: antibacterial humoral response; antifungal humoral response; antimicrobial humoral immune response mediated by antimicrobial peptide; antimicrobial humoral response; cellular protein metabolic process; defense response to Gram-negative bacterium; humoral immune response; innate immune response in mucosa; ion transport; iron assimilation by chelation and transport; killing of cells of other organism; membrane disruption in other organism; negative regulation by host of viral process; negative regulation of apoptosis; negative regulation of ATPase activity; negative regulation of cysteine-type endopeptidase activity; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of osteoclast development; negative regulation of single-species biofilm formation in or on host organism; negative regulation of tumor necrosis factor (ligand) superfamily member 11 production; negative regulation of viral genome replication; negative regulation of viral process; neutrophil degranulation; ossification; positive regulation of bone mineralization involved in bone maturation; positive regulation of chondrocyte proliferation; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of NF-kappaB transcription factor activity; positive regulation of osteoblast differentiation; positive regulation of osteoblast proliferation; positive regulation of protein serine/threonine kinase activity; positive regulation of toll-like receptor 4 signaling pathway; proteolysis; regulation of cytokine production; regulation of tumor necrosis factor production; retinal homeostasis; transcription, DNA-dependent
Research Articles on LTF
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Product Notes
The LTF ltf (Catalog #AAA2025866) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Lactoferrin (LTF) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lactoferrin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the LTF ltf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-LYLG SGYFTAIQNL RKSEEEVAAR RARVVWCAVG EQELRKCNQW SGLSEGSVTC SSASTTEDCI ALVLKGEADA MSLDGGYVYT AGKCGLVPVL AENYKSQQSS DPDPNCVDR. It is sometimes possible for the material contained within the vial of "Lactoferrin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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