Western Blot (WB)
(WB Suggested Anti-L3MBTL2 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
Rabbit L3MBTL2 Polyclonal Antibody | anti-L3MBTL2 antibody
L3MBTL2 antibody - C-terminal region
Gene Names
L3MBTL2; L3MBT; H-l(3)mbt-l
Reactivity
Cow, Dog, Horse, Human, Pig
Applications
Western Blot
Purity
Protein A purified
Synonyms
L3MBTL2; Polyclonal Antibody; L3MBTL2 antibody - C-terminal region; anti-L3MBTL2 antibody
Host
Rabbit
Reactivity
Cow, Dog, Horse, Human, Pig
Clonality
Polyclonal
Purity/Purification
Protein A purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: LLEDDPQGARKISSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVEN
Sequence Length
705
Applicable Applications for anti-L3MBTL2 antibody
Western Blot (WB)
Homology
Cow: 85%; Dog: 85%; Horse: 85%; Human: 100%; Pig: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-L3MBTL2 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
Western Blot (WB)
(WB Suggested Anti-L3MBTL2 Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T)
Related Product Information for anti-L3MBTL2 antibody
This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
Target Description: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
Product Categories/Family for anti-L3MBTL2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
79kDa
NCBI Official Full Name
lethal(3)malignant brain tumor-like protein 2
NCBI Official Synonym Full Names
L3MBTL histone methyl-lysine binding protein 2
NCBI Official Symbol
L3MBTL2
NCBI Official Synonym Symbols
L3MBT; H-l(3)mbt-l
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 2
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 2
Protein Family
UniProt Gene Name
L3MBTL2
UniProt Synonym Gene Names
H-l(3)mbt-like protein 2
UniProt Entry Name
LMBL2_HUMAN
Uniprot Description
Function: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. Ref.12
Subunit structure: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
Subcellular location: Nucleus
Probable.
Sequence similarities: Contains 1 FCS-type zinc finger.Contains 4 MBT repeats.
Sequence caution: The sequence BAB84917.1 differs from that shown. Reason: Intron retention.The sequence BAC04936.1 differs from that shown. Reason: Intron retention.
Research Articles on L3MBTL2
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Product Notes
The L3MBTL2 l3mbtl2 (Catalog #AAA3204775) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The L3MBTL2 antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's L3MBTL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the L3MBTL2 l3mbtl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LLEDDPQGAR KISSEPVPGE IIAVRVKEEH LDVASPDKAS SPELPVSVEN. It is sometimes possible for the material contained within the vial of "L3MBTL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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