Rabbit KU80 Polyclonal Antibody | anti-KU80 antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KU80 Polyclonal Antibody

• Gene Names: KU80; ARABIDOPSIS THALIANA KU80 HOMOLOG; ATKU80; KU80-LIKE PROTEIN; T2J15.4
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: KU80; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KU80 Polyclonal Antibody; KU80 Antibody; ATP-dependent DNA helicase 2 subunit KU80; EC 3.6.4.12; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80kDa subunit; KU80 At1g48050 F21D18.26 T2J15.4; anti-KU80 antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-KU80 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana KU80 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 18402015
• NCBI GeneID: 841223
• NCBI Accession #: NP_564520.1
• NCBI GenBank Nucleotide #: NM_103701.2
• UniProt Accession #: Q9FQ09; Q9C7Z3; Q9LNF5
• Molecular Weight: 76,688 Da
• NCBI Official Full Name: Ku80 family protein
• NCBI Official Symbol: KU80
• NCBI Official Synonym Symbols: ARABIDOPSIS THALIANA KU80 HOMOLOG; ATKU80; KU80-LIKE PROTEIN; T2J15.4
• NCBI Protein Information: Ku80 family protein
• UniProt Protein Name: ATP-dependent DNA helicase 2 subunit KU80
• Protein Family: ATP-dependent DNA helicase
• UniProt Gene Name: KU80

NCBI Description

Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.

Uniprot Description

Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase. Binds to and recombines double-stranded T-DNA molecules.