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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7129195(KLRF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit anti-Human KLRF1 Polyclonal Antibody | anti-KLRF1 antibody

KLRF1 Antibody

Gene Names
KLRF1; NKp80; CLEC5C
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
KLRF1; Polyclonal Antibody; KLRF1 Antibody; killer cell lectin-like receptor subfamily F; member 1; anti-KLRF1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-KLRF1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human KLRF1
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7129195(KLRF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7129195(KLRF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7129195(KLRF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7129195(KLRF1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human bladder carcinoma tissue, Primary antibody: MBS7129195(KLRF1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

SDS-Page (Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Human bladder carcinoma tissue, Primary antibody: MBS7129195(KLRF1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)
Product Categories/Family for anti-KLRF1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,666 Da
NCBI Official Full Name
killer cell lectin-like receptor subfamily F member 1
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily F, member 1
NCBI Official Symbol
KLRF1
NCBI Official Synonym Symbols
NKp80; CLEC5C
NCBI Protein Information
killer cell lectin-like receptor subfamily F member 1; lectin-like receptor F1; activating coreceptor NKp80; killer cell lectin-like receptor F1; C-type lectin domain family 5 member C
UniProt Protein Name
Killer cell lectin-like receptor subfamily F member 1
UniProt Gene Name
KLRF1
UniProt Synonym Gene Names
CLEC5C; ML; Lectin-like receptor F1
UniProt Entry Name
KLRF1_HUMAN

NCBI Description

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]

Uniprot Description

Function: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.

Subunit structure: Homodimer. Ref.3

Subcellular location: Membrane; Single-pass type II membrane protein

Potential.

Tissue specificity: Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. Ref.1

Sequence similarities: Contains 1 C-type lectin domain.

Research Articles on KLRF1

Similar Products

Product Notes

The KLRF1 klrf1 (Catalog #AAA7129195) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLRF1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLRF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the KLRF1 klrf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLRF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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