Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western blot analysis of KLRC2 Antibody (N-term) in CEM cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Rabbit anti-Human KLRC2 Polyclonal Antibody | anti-KLRC2 antibody

KLRC2, NT (Killer Cell Lectin-like Receptor Subfamily C Member 2, CD159 Antigen-like Family Member C, CD159c, MGC138244, NK Cell Receptor C, NKG2C, NKG2-C Activating NK Receptor, NKG2-C Type II Integral Membrane Protein) (APC)

Gene Names
KLRC2; NKG2C; CD159c; NKG2-C
Reactivity
Human
Applications
Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
KLRC2; Polyclonal Antibody; NT (Killer Cell Lectin-like Receptor Subfamily C Member 2; CD159 Antigen-like Family Member C; CD159c; MGC138244; NK Cell Receptor C; NKG2C; NKG2-C Activating NK Receptor; NKG2-C Type II Integral Membrane Protein) (APC); anti-KLRC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human KLRC2.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-KLRC2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the N-term region of human KLRC2 (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of KLRC2 Antibody (N-term) in CEM cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of KLRC2 Antibody (N-term) in CEM cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Western Blot (WB)

(Western blot analysis of KLRC2 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of KLRC2 Antibody (N-term) in HL-60 cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Western Blot (WB)

(Western blot analysis of KLRC2 Antibody (N-term) in K562 cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of KLRC2 Antibody (N-term) in K562 cell line lysates (35ug/lane). KLRC2 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(KLRC2 Antibody (N-term) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (KLRC2 Antibody (N-term) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS)

(KLRC2 Antibody (N-term) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (KLRC2 Antibody (N-term) flow cytometric analysis of HL60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-KLRC2 antibody
References
1. Seo, J., et.al., Tissue Antigens 70(4), 307-313 (2007). 2. Park, K.S., et.al., Tissue Antigens 72(4), 342-346 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,072 Da
NCBI Official Full Name
NKG2-C type II integral membrane protein
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily C, member 2
NCBI Official Symbol
KLRC2
NCBI Official Synonym Symbols
NKG2C; CD159c; NKG2-C
NCBI Protein Information
NKG2-C type II integral membrane protein; CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor
UniProt Protein Name
NKG2-C type II integral membrane protein
UniProt Gene Name
KLRC2
UniProt Synonym Gene Names
NKG2C
UniProt Entry Name
NKG2C_HUMAN

NCBI Description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

KLRC2: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; transmembrane receptor activity; carbohydrate binding

Biological Process: natural killer cell mediated immunity; cellular defense response; innate immune response; signal transduction

Research Articles on KLRC2

Similar Products

Product Notes

The KLRC2 klrc2 (Catalog #AAA6484526) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLRC2, NT (Killer Cell Lectin-like Receptor Subfamily C Member 2, CD159 Antigen-like Family Member C, CD159c, MGC138244, NK Cell Receptor C, NKG2C, NKG2-C Activating NK Receptor, NKG2-C Type II Integral Membrane Protein) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLRC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KLRC2 klrc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLRC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.