Rabbit Klp10A Polyclonal Antibody | anti-Klp10A antibody

Rabbit anti-Drosophila melanogaster (Fruit fly) Klp10A Polyclonal Antibody

• Gene Names: Klp10A; anon-WO03040301.142; CG1453; DmCG1453; DmelCG1453; DmKlp10A; DmKLP10A; KIF 2A; Kif2A; KIF2A/B/C; klp10A; KLP10a; KLP10A
• Reactivity: Drosophila melanogaster (Fruit fly)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: Klp10A; Polyclonal Antibody; Rabbit anti-Drosophila melanogaster (Fruit fly) Klp10A Polyclonal Antibody; Klp10A Antibody; Kinesin-like protein Klp10A; Kinesin-like protein at cytological position 10A; Klp10A CG1453; anti-Klp10A antibody

• Host: Rabbit
• Reactivity: Drosophila melanogaster (Fruit fly)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-Klp10A antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Drosophila melanogaster (Fruit fly) Klp10A protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 665390686
• NCBI GeneID: 32049
• NCBI Accession #: NP_001285109.1
• NCBI GenBank Nucleotide #: NM_001298180.1
• UniProt Accession #: Q960Z0
• Molecular Weight: 88,672 Da
• NCBI Official Full Name: Kinesin-like protein at 10A, isoform F
• NCBI Official Synonym Full Names: Kinesin-like protein at 10A
• NCBI Official Symbol: Klp10A
• NCBI Official Synonym Symbols: anon-WO03040301.142; CG1453; DmCG1453; DmelCG1453; DmKlp10A; DmKLP10A; KIF 2A; Kif2A; KIF2A/B/C; klp10A; KLP10a; KLP10A
• NCBI Protein Information: CG1453 gene product from transcript CG1453-RF
• UniProt Protein Name: Kinesin-like protein Klp10A
• Protein Family: Kinesin-like protein
• UniProt Gene Name: Klp10A

Uniprot Description

Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a "poleward flux" (PubMed:14681690, PubMed:20946984, PubMed:24100293). Involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara-expressing endosomes to the pIIa daughter cell but not to the pIIb cell. Klp98A targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division. During late cytokinesis, central spindle asymmetry is generated by enrichment of Patronin on the pIIb side which protects microtubules from depolymerization by Klp10A while unprotected microtubules on the pIIa side are disassembled by Klp10A, leading to the asymmetric delivery of Sara-expressing endosomes to the pIIa daughter cell (PubMed:26659188).