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Rabbit KLK4 Polyclonal Antibody | anti-KLK4 antibody

KLK4 Polyclonal Antibody

Gene Names
KLK4; ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; MGC116827; MGC116828
Applications
Immunoblot, Western Blot
Synonyms
KLK4; Polyclonal Antibody; KLK4 Polyclonal Antibody; anti-KLK4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
KLK4 [This antibody recognizes aa 242-254 of human KLK4 (also known as KLK-L1), one of the many kallikrein serine proteases associated with carcinogenesis.]
This antibody recognizes the gene product hk4 of human KLK4 (also known as KLK-L1), one of the many kallikrein serine proteases associated with carcinogenesis. KLK4 is upregulated by androgens and progestins and has been associated with prostate and breast cancers and possibly with other cancers.
Form/Format
100 ug affinity-purified antibody in PBS, pH 7.4.
Applicable Applications for anti-KLK4 antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 39 kD is detected.
Antigen
Peptide corresponding to aa 242-254 of human KLK4 protein.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
Product Categories/Family for anti-KLK4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,053 Da
NCBI Official Full Name
kallikrein-4 preproprotein
NCBI Official Synonym Full Names
kallikrein-related peptidase 4
NCBI Official Symbol
KLK4
NCBI Official Synonym Symbols
ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; MGC116827; MGC116828
NCBI Protein Information
kallikrein-4; prostase; serine protease 17; kallikrein-like protein 1; androgen-regulated message 1; enamel matrix serine protease 1; enamel matrix serine proteinase 1
UniProt Protein Name
Kallikrein-related peptidase 4
Protein Family
UniProt Gene Name
KLK4
UniProt Entry Name
Q4VB17_HUMAN

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq]

Uniprot Description

Sequence similarities: Belongs to the peptidase S1 family. RuleBase RU000360

Research Articles on KLK4

Similar Products

Product Notes

The KLK4 klk4 (Catalog #AAA194284) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's KLK4 can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 39 kD is detected. Researchers should empirically determine the suitability of the KLK4 klk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLK4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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