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Rabbit anti-Human KLK12 Polyclonal Antibody | anti-KLK12 antibody

KLK12 antibody

Gene Names
KLK12; KLKL5; KLK-L5
Reactivity
Human
Applications
Western Blot
Purity
KLK12 antibody was purified by affinity chromatography.
Synonyms
KLK12; Polyclonal Antibody; KLK12 antibody; Polyclonal KLK12; Anti-KLK12; KLK-12; KLK 12; KLK -12; Kallikrein 12; anti-KLK12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
KLK12 antibody was purified by affinity chromatography.
Form/Format
Affinity purified IgG supplied in PBS with 0.02% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
111
Applicable Applications for anti-KLK12 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1,000
Biological Significance
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. A novel KLK gene, KLK12, is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, breast, thyroid, and trachea. It has applications as a novel cancer biomarker.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
KLK12 antibody was raised in rabbit using residues 236-248 [KYVDWIRMIMRNN] of the human KLK12 protein as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-KLK12 antibody
Affinity purified Rabbit polyclonal KLK12 antibody
Product Categories/Family for anti-KLK12 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,984 Da
NCBI Official Full Name
kallikrein-12 isoform 3
NCBI Official Synonym Full Names
kallikrein-related peptidase 12
NCBI Official Symbol
KLK12
NCBI Official Synonym Symbols
KLKL5; KLK-L5
NCBI Protein Information
kallikrein-12
UniProt Protein Name
Kallikrein-12
Protein Family
UniProt Gene Name
KLK12
UniProt Synonym Gene Names
KLKL5; KLK-L5
UniProt Entry Name
KLK12_HUMAN

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

KLK12: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.21.-; Secreted; Protease; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space

Molecular Function: peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis

Research Articles on KLK12

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Product Notes

The KLK12 klk12 (Catalog #AAA534503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLK12 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLK12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the KLK12 klk12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLK12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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