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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using KLK1 Polyclonal Antibody at dilution 1:40)

Rabbit KLK1 Polyclonal Antibody | anti-KLK1 antibody

KLK1 Polyclonal Antibody

Gene Names
KLK1; hK1; KLKR; Klk6
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
KLK1; Polyclonal Antibody; KLK1 Polyclonal Antibody; hK1; KLKR; Klk6; anti-KLK1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.7mg/mL (varies by lot)
Sequence Length
262
Applicable Applications for anti-KLK1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant protein of human KLK1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using KLK1 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using KLK1 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using KLK1 Polyclonal Antibody at dilution 1:40)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using KLK1 Polyclonal Antibody at dilution 1:40)
Related Product Information for anti-KLK1 antibody
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Product Categories/Family for anti-KLK1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,835 Da
NCBI Official Full Name
kallikrein-1 preproprotein
NCBI Official Synonym Full Names
kallikrein 1
NCBI Official Symbol
KLK1
NCBI Official Synonym Symbols
hK1; KLKR; Klk6
NCBI Protein Information
kallikrein-1; glandular kallikrein 1; kallikrein 1, renal/pancreas/salivary; kallikrein serine protease 1; kidney/pancreas/salivary gland kallikrein; tissue kallikrein
UniProt Protein Name
Kallikrein-1
Protein Family
UniProt Gene Name
KLK1
UniProt Entry Name
KLK1_HUMAN

NCBI Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008]

Uniprot Description

KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.21.35

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: nucleus

Molecular Function: serine-type endopeptidase activity

Biological Process: proteolysis

Disease: Kallikrein, Decreased Urinary Activity Of

Research Articles on KLK1

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Product Notes

The KLK1 klk1 (Catalog #AAA2521964) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLK1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KLK1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the KLK1 klk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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